Ulyanovsk Medico-biological Journal

PHYSIOLOGY

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DOI 10.34014/2227-1848-2022-2-81-91

ORGANIZATION OF BRAIN ACTIVITY IN MEN AND WOMEN DURING MENTAL PRONUNCIATION OF WORDS

E.M. Krivko, O.M. Bakhtin, V.N. Kiroy, D.M. Lazurenko, D.G. Shaposhnikov

Southern Federal University, Rostov-on-Don, Russia

 

The purpose of the study is to examine gender differences associated with the mental pronunciation of words in EEG coherence patterns.

Materials and Methods. The authors studied the impact of gender differences on the characteristics of EEG spatial synchronization patterns associated with the mental pronunciation of words denoting direction: up, down, left, right, forward, backward. The study enrolled 10 boys and 10 girls, aged 21±3.

Results. The dominance of the left hemisphere was observed in young men, while the right hemisphere dominated in girls. Specific patterns of EEG coherence are formed in both left and right hemispheres. Discrimination of mentally pronounced words according to the EEG coherence values in young men is effectively implemented according to coherence patterns, which form separately in both left and right hemispheres, whereas in girls the coherence patterns of both hemispheres should be taken into account. Gender peculiarities in the structural and functional organization of the brain and the characteristics of its bioelectrical activity should not be underestimated, in particular, when developing a BCI based on EEG and inner speech. It is known that the internal (mental) pronunciation of words is reflected both in the cortical and superficially recorded bioelectrical activity of the brain. EEG recording of the activity has obvious advantages. However, so far little is known about manifestation of inner speech and its characteristics with respect to gender.

Conclusion. The results obtained confirm gender differences in the EEG characteristics of the brain during the mental pronunciation of words denoting directions.

Key words: EEG, verbal activity, coherence, gender characteristics, inner speech.

 

References

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  3. Cooney C., Folli R., Coyle D. Neurolinguistics research advancing development of a direct-speech brain-computer interface. IScience. 2018; 8: 103–125.

  4. Kiroy V.N., Bakhtin O.M., Minyaeva N.R., Lazurenko D.M., Aslanyan, E.V., Kiroy R.I. Elektrograficheskie korrelyaty vnutrenney rechi [Electrographic correlates of inner speech]. Zhurn. vyssh. nerv. deyat. 2015; 65 (5): 616–625 (in Russian).

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  6. De Lima Xavier L., Hanekamp S., Simonyan K. Sexual dimorphism within brain regions controlling speech production. Frontiers in neuroscience. 2019; 13: 795.

  7. McGlone J. Sex differences in functional brain asymmetry. Cortex. 1978; 14 (1): 122–128.

  8. McGlone J. Sex differences in human brain asymmetry: A critical survey. Behavioral and brain sciences. 1980; 3 (2): 215–227.

  9. Obleser J. Gender differences in functional hemispheric asymmetry during processing of vowels as reflected by the human brain magnetic response. Neuroscience letters. 2001; 314 (3): 131–134.

  10. Frost J.A. Language processing is strongly left lateralized in both sexes: Evidence from functional MRI. Brain. 1999; 122 (2): 199–208.

  11. Gong G., He Y., Evans A.C. Brain connectivity: gender makes a difference. The Neuroscientist. 2011; 17 (5): 575–591.

  12. Bogolepova I.N., Agapov P.A., Malofeeva I.G., Piletskaya I.A. Mezhpolusharnaya asimmetriya peredney limbicheskoy oblasti kory mozga cheloveka [Interhemispheric asymmetry of the anterior limbic cortex]. Mezhdunarodnyy zhurnal prikladnykh i fundamental'nykh issledovaniy. 2021; 5: 7–11 (in Russian).

  13. Moctezuma L.A., Molinas M. Sex differences observed in a study of EEG of linguistic activity and resting-state: Exploring optimal EEG channel configurations. 7th International Winter Conference on Brain-Computer Interface (BCI). 2019; 6: 1–6.

  14. Hirnstein M., Hugdahl K., Hausmann M. Cognitive sex differences and hemispheric asymmetry: A critical review of 40 years of research. Laterality: Asymmetries of Body, Brain and Cognition. 2019; 24 (2): 204–252.

  15. Ingalhalikar M. Reply to Joel and Tarrasch: On misreading and shooting the messenger. Proceedings of the National Academy of Sciences. 2014; 111 (6): E638.

  16. Scheuringer A., Harris T.A., Pletzer B. Recruiting the right hemisphere: Sex differences in inter-hemispheric communication during semantic verbal fluency. Brain and Language. 2020; 207.

  17. Gur R.C., Alsop D., Glahn D., Petty R., Swanson C.L., Maldjian J.A. An fMRI study of sex differences in regional activation to a verbal and a spatial task. Brain Lang. 2000; 74: 157–170.

  18. Packheiser J. A large-scale estimate on the relationship between language and motor lateralization. Scientific reports. 2020; 10 (1): 1–10.

  19. Lenroot R.K., Giedd J.N. Sex differences in the adolescent brain. Brain and cognition. 2010; 72 (1): 46–55.

  20. Hiscock M. Is there a sex difference in human laterality? II. An exhaustive survey of visual laterality studies from six neuropsychology journals. Journal of Clinical and Experimental Neuropsychology. 1995; 17 (4): 590–610.

  21. Vol'f N.V. Polovye razlichiya funktsional'noy organizatsii protsessov polusharnoy obrabotki rechevoy informatsii [Gender differences in the functional organization of the hemispheric processing of speech information]. Rostov-na-Donu: TsVVR; 2000. 240 (in Russian).

  22. Langrova J. Gender impact on electrophysiological activity of the brain. Physiological research. 2012; 61.

  23. Thornton D. Sex differences in early sensorimotor processing for speech discrimination. Scientific reports. 2019; 9 (1): 1–13.

  24. Peper J.S. Sex steroids and connectivity in the human brain: a review of neuroimaging studies. Psychoneuroendocrinology. 2011; 36 (8): 1101–1113.

  25. Sato M. The neurobiology of sex differences during language processing in healthy adults: A systematic review and a meta-analysis. Neuropsychologia. 2020; 140.

  26. Qureshi M.N.I. Multiclass classification of word imagination speech with hybrid connectivity features. Transactions on Biomedical Engineering. 2017; 65 (10): 2168–2177.

  27. Martin S. Decoding spectrotemporal features of overt and covert speech from the human cortex. Frontiers in neuroengineering. 2014; 7: 14.

  28. Muller L. Spatial resolution dependence on spectral frequency in human speech cortex electrocorticographyю. Journal of neural engineering. 2016; 13 (5): 056013.

  29. Bakhtin O.M., Krivko E.M., Kiroy V.N. Elektromiograficheskie komponenty, assotsiirovannye s vnutrenney rech'yu [Electromyographic components associated with inner speech]. Zhurnal mediko-biologicheskikh issledovaniy. 2020; 8 (2): 111–120 (in Russian).

  30. Friederici A.D. The brain basis of language processing: from structure to function. Physiological reviews. 2011; 91 (4): 1357–1392.

  31. Vorontsova D. Silent EEG-Speech Recognition Using Convolutional and Recurrent Neural Network with 85 % Accuracy of 9 Words Classification. Sensors. 2021; 21 (20): 6744.

  32. Simmonds A.J. Parallel systems in the control of speech. Human brain mapping. 2014; 35 (5): 1930–1943.

  33. Silbert L.J. Coupled neural systems underlie the production and comprehension of naturalistic narrative speech. Proceedings of the National Academy of Sciences. 2014; 111 (43): E4687–E4696.

  34. Geranmayeh F. Overlapping networks engaged during spoken language production and its cognitive control. Journal of Neuroscience. 2014; 34 (26): 8728–8740.

  35. Simonyan K., Fuertinger S. Speech networks at rest and in action: interactions between functional brain networks controlling speech production. Journal of neurophysiology. 2015; 113 (7): 2967–2978.

 Received 24 January 2022; accepted 03 March 2022.

 

Information about the authors

Krivko Elena Mikhaylovna, Junior Researcher, Research Technological Center for Neurotechnologies, Southern Federal University. 344090, Russia, Rostov-on-Don, Stachki Ave., 194; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0001-9003-4690

Bakhtin Oleg Marksovich, Candidate of Sciences (Biology), Senior Researcher, Research Technological Center for Neurotechnologies, Southern Federal University. 344090, Russia, Rostov-on-Don, Stachki Ave., 194; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0003-2164-7885

Kiroy Valeriy Nikolaevich, Professor, Doctor of Sciences (Biology), Chief Researcher, Head of the Research Technological Center for Neurotechnologies, Southern Federal University. 344090, Russia, Rostov-on-Don, Stachki Ave., 194; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0003-3560-9935

Lazurenko Dmitriy Mikhaylovich, Leading Researcher, Research Technological Center for Neurotech-
nologies, Southern Federal University. 344090, Russia, Rostov-on-Don, Stachki Ave., 194; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0001-8704-1275

Shaposhnikov Dmitriy Grigor'evich, Leading Researcher, Research Technological Center for Neurotechnologies, Southern Federal University. 344090, Russia, Rostov-on-Don, Stachki Ave., 194; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0002-1797-6232

 

For citation

Krivko E.M., Bakhtin O.M., Kiroy V.N., Lazurenko D.M., Shaposhnikov D.G. Organizatsiya mozgovoy aktivnosti pri myslennom progovarivanii slov u muzhchin i zhenshchin [Organization of brain activity in men and women during mental pronunciation of words]. Ul'yanovskiy mediko-biologicheskiy zhurnal. 2022; 2: 81–91. DOI: 10.34014/2227-1848-2022-2-81-91 (in Russian).

 

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DOI 10.34014/2227-1848-2022-2-81-91

ОРГАНИЗАЦИЯ МОЗГОВОЙ АКТИВНОСТИ ПРИ МЫСЛЕННОМ ПРОГОВАРИВАНИИ СЛОВ У МУЖЧИН И ЖЕНЩИН

Е.М. Кривко, О.М. Бахтин, В.Н. Кирой, Д.М. Лазуренко, Д.Г. Шапошников

ФГАОУ ВО «Южный федеральный университет», г. Ростов-на-Дону, Россия

 

Цель работы – изучение гендерных различий в паттернах когерентности ЭЭГ, связанных с мысленным проговариванием слов.

Материалы и методы. На 10 юношах и 10 девушках в возрасте 21±0,3 года исследовалось влияние гендерных различий на характеристики паттернов пространственной синхронизации ЭЭГ, ассоциированных с мысленным проговариванием слов, обозначающих направления в пространстве: вверх, вниз, влево, вправо, вперед, назад.

Результаты. Показано, что у юношей наблюдается доминирование левого, тогда как у девушек – правого полушария, где формируются специфические паттерны когерентности ЭЭГ. Дискриминация мысленно произносимых слов по значениям когерентности ЭЭГ у юношей эффективно реализуется по паттернам когерентности, формирующимся отдельно как в левом, так и правом полушариях, тогда как у девушек – только при учете паттернов когерентности обоих полушарий. Наличие гендерных особенностей в структурно-функциональной организации мозга и характеристиках его биоэлектрической активности нельзя недооценивать, в частности при разработке ИМК на базе ЭЭГ и внутренней речи. Известно, что внутреннее (мысленное) проговаривание слов отражается как в собственно кортикальной, так и в поверхностно регистрируемой биоэлектрической активности мозга. Регистрация активности с использованием метода ЭЭГ имеет очевидные преимущества, однако до настоящего времени практически не известно, как внутренняя речь и ее характеристики проявляются с учетом гендерных различий.

Выводы. Полученные результаты подтверждают наличие гендерных различий в ЭЭГ-характеристиках мозга при мысленном произнесения слов, обозначающих направления в пространстве.

Ключевые слова: ЭЭГ, вербальная активность, когерентность, гендерные особенности, внутренняя речь.

 

Литература

  1. Выготский Л.С. Мышление и речь: сборник. Москва; 2020. 250.

  2. Martin S., Millán José del R., Knight R., Brian T., Pasley N. The use of intracranial recordings to decode human language: Challenges and opportunities. Brain & Language. 2019; 193: 73–83.

  3. Cooney C., Folli R., Coyle D. Neurolinguistics research advancing development of a direct-speech brain-computer interface. IScience. 2018; 8: 103–125.

  4. Кирой В.Н., Бахтин О.М., Миняева Н.Р., Лазуренко Д.М., Асланян Е.В., Кирой Р.И. Электрографические корреляты внутренней речи. Журн. высш. нерв. деят. 2015; 65 (5): 616–625.

  5. Kiroy V.N., Bakhtin O.M., Krivko E.M., Lazurenko D.M., Aslanyan E.V., Shaposhnikov D.G., Shcherban I.V. Spoken and Inner Speech-related EEG Connectivity in Different Spatial Direction. Biomedical Signal Processing and Control. 2022; 71: 103–224. DOI: https://doi.org/10.1016/j.bspc.2021.103224.

  6. De Lima Xavier L., Hanekamp S., Simonyan K. Sexual dimorphism within brain regions controlling speech production. Frontiers in neuroscience. 2019; 13: 795.

  7. McGlone J. Sex differences in functional brain asymmetry. Cortex. 1978; 14 (1): 122–128.

  8. McGlone J. Sex differences in human brain asymmetry: A critical survey. Behavioral and brain sciences. 1980; 3 (2): 215–227.

  9. Obleser J. Gender differences in functional hemispheric asymmetry during processing of vowels as reflected by the human brain magnetic response. Neuroscience letters. 2001; 314 (3): 131–134.

  10. Frost J.A. Language processing is strongly left lateralized in both sexes: Evidence from functional MRI. Brain. 1999; 122 (2): 199–208.

  11. Gong G., He Y., Evans A.C. Brain connectivity: gender makes a difference. The Neuroscientist. 2011; 17 (5): 575–591.

  12. Боголепова И.Н., Агапов П.А., Малофеева И.Г., Пилецкая И.А. Межполушарная асимметрия передней лимбической области коры мозга человека. Международный журнал прикладных и фундаментальных исследований. 2021; 5: 7–11.

  13. Moctezuma L.A., Molinas M. Sex differences observed in a study of EEG of linguistic activity and resting-state: Exploring optimal EEG channel configurations. 7th International Winter Conference on Brain-Computer Interface (BCI). 2019; 6: 1–6.

  14. Hirnstein M., Hugdahl K., Hausmann M. Cognitive sex differences and hemispheric asymmetry: A critical review of 40 years of research. Laterality: Asymmetries of Body, Brain and Cognition. 2019; 24 (2): 204–252.

  15. Ingalhalikar M. Reply to Joel and Tarrasch: On misreading and shooting the messenger. Proceedings of the National Academy of Sciences. 2014; 111 (6): E638.

  16. Scheuringer A., Harris T.A., Pletzer B. Recruiting the right hemisphere: Sex differences in inter-hemispheric communication during semantic verbal fluency. Brain and Language. 2020; 207.

  17. Gur R.C., Alsop D., Glahn D., Petty R., Swanson C.L., Maldjian J.A. An fMRI study of sex differences in regional activation to a verbal and a spatial task. Brain Lang. 2000; 74: 157–170.

  18. Packheiser J. A large-scale estimate on the relationship between language and motor lateralization. Scientific reports. 2020; 10 (1): 1–10.

  19. Lenroot R.K., Giedd J.N. Sex differences in the adolescent brain. Brain and cognition. 2010; 72 (1): 46–55.

  20. Hiscock M. Is there a sex difference in human laterality? II. An exhaustive survey of visual laterality studies from six neuropsychology journals. Journal of Clinical and Experimental Neuropsychology. 1995; 17 (4): 590–610.

  21. Вольф Н.В. Половые различия функциональной организации процессов полушарной обработки речевой информации. Ростов-на-Дону: ЦВВР; 2000. 240.

  22. Langrova J. Gender impact on electrophysiological activity of the brain. Physiological research. 2012; 61.

  23. Thornton D. Sex differences in early sensorimotor processing for speech discrimination. Scientific reports. 2019; 9 (1): 1–13.

  24. Peper J.S. Sex steroids and connectivity in the human brain: a review of neuroimaging studies. Psychoneuroendocrinology. 2011; 36 (8): 1101–1113.

  25. Sato M. The neurobiology of sex differences during language processing in healthy adults: A systematic review and a meta-analysis. Neuropsychologia. 2020; 140.

  26. Qureshi M.N.I. Multiclass classification of word imagination speech with hybrid connectivity features. Transactions on Biomedical Engineering. 2017; 65 (10): 2168–2177.

  27. Martin S. Decoding spectrotemporal features of overt and covert speech from the human cortex. Frontiers in neuroengineering. 2014; 7: 14.

  28. Muller L. Spatial resolution dependence on spectral frequency in human speech cortex electrocorticographyю. Journal of neural engineering. 2016; 13 (5): 056013.

  29. Бахтин О.М., Кривко Е.М., Кирой В.Н. Электромиографические компоненты, ассоциированные с внутренней речью. Журнал медико-биологических исследований. 2020; 8 (2): 111–120.

  30. Friederici A.D. The brain basis of language processing: from structure to function. Physiological reviews. 2011; 91 (4): 1357–1392.

  31. Vorontsova D. Silent EEG-Speech Recognition Using Convolutional and Recurrent Neural Network with 85 % Accuracy of 9 Words Classification. Sensors. 2021; 21 (20): 6744.

  32. Simmonds A.J. Parallel systems in the control of speech. Human brain mapping. 2014; 35 (5): 1930–1943.

  33. Silbert L.J. Coupled neural systems underlie the production and comprehension of naturalistic narrative speech. Proceedings of the National Academy of Sciences. 2014; 111 (43): E4687–E4696.

  34. Geranmayeh F. Overlapping networks engaged during spoken language production and its cognitive control. Journal of Neuroscience. 2014; 34 (26): 8728–8740.

  35. Simonyan K., Fuertinger S. Speech networks at rest and in action: interactions between functional brain networks controlling speech production. Journal of neurophysiology. 2015; 113 (7): 2967–2978.

 Поступила в редакцию 24.01.2022; принята 03.03.2022.

 

Авторский коллектив

Кривко Елена Михайловна – младший научный сотрудник Научно-исследовательского технологического центра нейротехнологий, ФГАОУ ВО «Южный федеральный университет». 344090, Россия, г. Ростов-на-Дону, пр-т Стачки, 194; е-mail: еThis email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0001-9003-4690

Бахтин Олег Марксович – кандидат биологических наук, старший научный сотрудник Научно-исследовательского технологического центра нейротехнологий, ФГАОУ ВО «Южный федеральный университет». 344090, Россия, г. Ростов-на-Дону, пр-т Стачки, 194; е-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0003-2164-7885

Кирой Валерий Николаевич – профессор, доктор биологических наук, главный научный сотрудник, руководитель Научно-исследовательского технологического центра нейротехнологий, ФГАОУ ВО «Южный федеральный университет». 344090, Россия, г. Ростов-на-Дону, пр-т Стачки, 194; е-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0003-3560-9935

Лазуренко Дмитрий Михайлович – ведущий научный сотрудник Научно-исследовательского технологического центра нейротехнологий, ФГАОУ ВО «Южный федеральный университет». 344090, Россия, г. Ростов-на-Дону, пр-т Стачки, 194; е-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0001-8704-1275

Шапошников Дмитрий Григорьевич – ведущий научный сотрудник Научно-исследовательского технологического центра нейротехнологий, ФГАОУ ВО «Южный федеральный университет». 344090, Россия, г. Ростов-на-Дону, пр-т Стачки, 194; е-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., ORCID ID: https://orcid.org/0000-0002-1797-6232

 

Образец цитирования

Кривко Е.М., Бахтин О.М., Кирой В.Н., Лазуренко Д.М., Шапошников Д.Г. Организация мозговой активности при мысленном проговаривании слов у мужчин и женщин. Ульяновский медико-биологический журнал. 2022; 2: 81–91. DOI: 10.34014/2227-1848-2022-2-81-91.