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DOI 10.34014/2227-1848-2020-4-19-29

USING VIRTUAL REALITY FOR PAIN MANAGEMENT IN CHILDREN

 

N.S. Bofanova, E.V. Petrova, V.B. Kalistratov, E.N. Nesterenko, D.I. Chizh

Penza State University, Penza, Russia

 

Virtual reality is a relatively new tool for human-computer interaction. A person becomes an active participant in a virtual world. Virtual reality has quickly become the research subject in various medical fields. For example, today many medical procedures are accompanied by severe pain syndrome and require pain relievers. Virtual reality as an effective non-pharmacological means of reducing pain may become a new way of pain management. Currently, there is not enough scientific papers on the efficacy of the method, which has become the reason for this literature review.

The goal of the paper is to analyze electronic databases and scientific literature on the topic over the past 5 years (from 2014 to 2019).

Virtual reality has been used to reduce pain in children (4 to 17 years old) in the following medical procedures: intravenous injections, care for burn wounds, wound dressing, drug blockade, vaccination, and acute pain syndrome. The results obtained show that virtual reality is an effective non-pharmacological method of pain management. However, there are still some unresolved questions on the interaction between virtual exposure and some pain killers. Moreover, it is also unclear what is more preferable: the initial use of virtual reality therapy followed by a standard therapy, or vice versa.

Conclusion. More research is needed to understand the impact of virtual reality in pediatrics on both acute pain and chronic pain.

Keywords: virtual reality, pain syndrome, pediatrics.

Conflict of interest. The authors declare no conflict of interest.

 

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28. Reger G.M., Koenen-Woods P., Zetocha K., Smolenski D.J., Holloway K.M., Rothbaum B.O. Randomized controlled trial of prolonged exposure using imaginal exposure vs. virtual reality exposure in active duty soldiers with deployment-related posttraumatic stress disorder (PTSD). J. Consult. Clin. Psychol. 2016; 84 (11): 946–959.

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Received 30 June 2020; accepted 12 September 2020.

 

Information about the authors

Bofanova Nataliya Sergeevna, Candidate of Sciences (Medicine), Associate Professor, Chair of Neurology, Neurosurgery and Psychiatry, Penza State University. 440026, Russia, Penza, Krasnaya St., 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-5455-4987.

Petrova Elena Vladimirovna, Candidate of Sciences (Medicine), Associate Professor, Head of the Chair of Neurology, Neurosurgery and Psychiatry, Penza State University. 440026, Russia, Penza, Krasnaya St., 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-5941-8300.

Kalistratov Vladimir Borisovich, Candidate of Sciences (Medicine), Associate Professor, Chair of Neurology, Neurosurgery and Psychiatry, Penza State University. 440026, Russia, Penza, Krasnaya St., 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-5851-857X.

Nesterenko Evgeniy Nikolaevich, Candidate of Sciences History), Senior Lecturer, Chair of Neurology, Neurosurgery and Psychiatry, Penza State University. 440026, Russia, Penza, Krasnaya St., 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-8990-3454.

Chizh Dar'ya Ivanovna, Teaching Assistant, Chair of Neurology, Neurosurgery and Psychiatry, Penza State University. 440026, Russia, Penza, Krasnaya St., 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-9958-4426.

 

For citation

Bofanova N.S., Petrova E.V., Kalistratov V.B., Nesterenko E.N., Chizh D.I. Primenenie tekhnologii virtual'noy real'nosti dlya lecheniya bolevogo sindroma u detey [Using virtual reality for pain management in children]. Ul'yanovskiy mediko-biologicheskiy zhurnal. 2020; 4: 19–29. DOI: 10.34014/2227-1848-2020-4-19-29 (in Russian).

 

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УДК 616.8-009.6

DOI 10.34014/2227-1848-2020-4-19-29

ПРИМЕНЕНИЕ ТЕХНОЛОГИИ ВИРТУАЛЬНОЙ РЕАЛЬНОСТИ ДЛЯ ЛЕЧЕНИЯ БОЛЕВОГО СИНДРОМА У ДЕТЕЙ

 

Н.С. Бофанова, Е.В. Петрова, В.Б. Калистратов, Е.Н. Нестеренко, Д.И. Чиж

ФГБОУ ВО «Пензенский государственный университет», г. Пенза, Россия

 

Виртуальная реальность – относительно новый инструмент взаимодействия человека с компьютером, когда человек становится активным участником виртуального мира. Виртуальная реальность быстро стала предметом исследования в разных медицинских областях. Так, например, сегодня многие медицинские процедуры сопровождаются выраженным болевым синдромом и требуют применения обезболивающих препаратов. Новым направлением в обезболивании может стать применение виртуальной реальности как эффективного нефармакологического средства уменьшения болевого синдрома. В настоящее время опубликовано недостаточно научных работ об эффективности этого метода, что стало причиной проведения данного литературного обзора.

Цель – анализ электронных баз данных и научной литературы за последние 5 лет (с 2014 по 2019 г.).

Виртуальная реальность использовалась для уменьшения болевого синдрома у детей (от 4 до 17 лет) при следующих процедурах: внутривенные инъекции, уход за ожоговыми ранами, перевязка ран, проведение медикаментозных блокад, вакцинация, а также при остром болевом синдроме. Результаты проанализированных исследований показывают, что виртуальная реальность является эффективным нефармакологическим методом уменьшения болевого синдрома. Однако остаются нерешенными вопросы о взаимодействии между виртуальным воздействием и некоторыми обезболивающими препаратами, также неясно, что является более предпочтительным: первоначальное применение терапии с помощью виртуальной реальности, а затем без нее или наоборот.

Выводы. Необходимо проведение дополнительных исследований для лучшего понимания влияния виртуальной реальности в педиатрии как на острый болевой синдром, так и на хроническую боль.

Ключевые слова: виртуальная реальность, болевой синдром, педиатрия.

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.

 

Литература

1. Данилов А.Б. Виртуальная реальность – метод лечения боли и аффективных нарушений. Лечение заболеваний нервной системы. М.: ООО «Неврология»; 2014: 11–17. URL: https://elibrary.ru/item.asp?id=22577472 (дата обращения: 11.12.2019).

2.  Кузьмина А.С. Виртуальная реальность как средство безопасного контакта с травмирующей реальностью в психотерапии. Вестник Российского университета дружбы народов. 2014; 3: 77–82. URL: https://elibrary.ru/item.asp?id=21970476 (дата обращения: 25.11.2019).

3.   Rothbaum B.O., Hodges L., Alarcon R., Ready D., Shahar F., Graap K., Pair J., Hebert P., Gotz D., Wills B., Baltzell D. Virtual reality exposure therapy for PTSD Vietnam Veterans: a case study. J. Trauma Stress. 1999; 12: 263–271.

4.  Iannicelli A.M., Vito D., Dodaro C.A., De Matteo P. Does virtual reality reduce pain in pediatric patients? A systematic review. Italian Journal of Pediatrics. 2019; 45: 171.

5.  Friedrichsdorf S.J., Postier A., Eull D., Weidner C., Foster L., Gilbert M., Campbell F. Pain Outcomes in a US Children's Hospital: A Prospective Cross-Sectional Survey. Hosp. Pediatr. 2015; 5 (1): 18–26.

6.  Shomaker K., Dutton S., Mark M. Pain prevalence and treatment patterns in a US Children's hospital. Hosp. Pediatr. 2015; 5: 363–370.

7.  McMurtry M., Riddell R.P., Taddio A., Racine N., Asmundson G.J., Noel M., Chambers C.T., Shah V. Far From "Just a Poke": Common Painful Needle Procedures and the Development of Needle Fear. Clin. J. Pain. 2015; 31 (10): 3–11.

8.  Birnie K.A., Chambers C.T., Fernandez C.V., Forgeron P.A., Latimer M.A., McGrath P.J., Cummings E.A., Finley G.A. Hospitalized children continue to report undertreated and preventable pain. Pain Res. Manag. 2014; 19: 198–204.

9.  Krauss B.S., Calligaris L., M. Green S., Barbi E. Current concepts in management of pain in children in the emergency department. Lancet. 2016; 387 (10013): 83–92.

10. Boutron I., Altman D.G., Moher D., Schulz K.F., Ravaud P., CONSORT NPT Group. CONSORT statement for randomized trials of nonpharmacologic treatments: a 2017 update and a CONSORT extension for nonpharmacologic trial abstracts. Ann. Intern. Med. 2017; 167: 40–47.

11.  Matsangidou M., Ang C.S., Sakel M. Clinical utility of virtual reality in pain management: a comprehensive research review. Br. J. Neurosci Nurs. 2017; 13: 133–143. DOI: 10.12968/BJNN.2017.13.3.133.

12.  Garrett B., Taverner T., Masinde W., Gromala D., Shaw C., Negraeff M. A rapid evidence assessment of immersive virtual reality as an adjunct therapy in acute pain management in clinical practice. Clin. J. Pain. 2014; 30: 1089–1098.

13.  Kenney M.S., Milling L.S. The effectiveness of virtual reality distraction for reducing pain: a meta-analysis. Psychol. Conscious Theory Res. Pract. 2016; 3: 199–210.

14. Cummings J.J., Bailenson J.N. How immersive is enough? A meta-analysis of the effect of immersive technology on user presence. Media Psychol. 2016; 19: 272–309.

15.  Weech S., Kenny S., Barnett-Cowan M. Presence and Cybersickness in Virtual Reality Are Negatively Related: A Review. Front. Psychol. 2019; 10.

16.  Hoffman H.G, Meyer W.J., Ramirez M., Roberts L., Seibel E.J., Atzori B., Sharar S.R., Patterson D.R. Feasibility of articulated arm mounted Oculus Rift Virtual Reality goggles for adjunctive pain control during occupational therapy in pediatric burn patients. Cyberpsychol. Behav. Soc. Netw. 2014; 17: 397–401.

17.  He H.G., Zhu L., Chan S.W.C., Liam J.L.W., Li H.C.W., Ko S.S., Klainin-Yobas P., Wang W. Therapeutic play intervention on children’s perioperative anxiety, negative emotional manifestation and postoperative pain: A randomized controlled trial. J. Adv. Nurs. 2015; 71: 1032–1043.

18.  Harvie D.S., Broecker M., Smith R.T., Meulders A., Madden V.J., Moseley G.L. Bogus visual feedback alters onset of movement-evoked pain in people with neck pain. Psychol. Sci. 2015; 26: 385–392. DOI: 10.1177/0956797614563339.

19. Chen K.B., Sesto M.E., Ponto K., Leonard J., Mason A., Vanderheiden G., Williams J., Radwin R.G. Use of virtual reality feedback for patients with chronic neck pain and kinesiophobia. IEEE Trans. Neural Syst. Rehabil. Eng. 2017; 25 (8): 1240–1248. DOI: 10.1109/TNSRE.2016.2621886.

20.  Simons L., Pielech M., Erpelding N., Linnman C., Moulton E., Sava S., Lebel A., Serrano P., Sethna N., Berde C. The responsive amygdala: Treatment-induced alterations in functional connectivity in pediatric complex regional pain syndrome. Pain. 2014; 155: 1727–1742.

21.  Meyns P., Pans L., Plasmans K., Heyrman L., Desloovere K., Molenaers G. The Effect of additional virtual reality training on balance in children with cerebral palsy after lower limb surgery: A feasibility study. Games Health J. 2017; 6: 39–48.

22.  Senkowski D., Heinz A. Chronic pain and distorted body image: Implications for multisensory feedback interventions. Neurosci Biobehav. Rev. 2016; 69: 252–259.

23.  Collado-Mateo D., Dominguez-Muñoz F.J., Adsuar J.C., Merellano-Navarro E., Gusi N. Exergames for women with fibromyalgia: A randomised controlled trial to evaluate the effects on mobility skills, balance and fear of falling. Peer J. 2017; 5: e3211.

24.  Oing T., Prescott J. Implementations of virtual reality for anxiety-related disorders: systematic review. JMIR Serious Games. 2018; 6: e10965.

25.  López G.C., Gómez A.R., Figueroa R.D., Baca X.D. Virtual reality exposure for trauma and stress-related disorders for city violence crime victims. Int. J. Child Health Hum. Dev. 2016; 9 (3): 315–322.

26.  Lindner P., Miloff A., Hamilton W., Reuterskiöld L., Andersson G., Powers M.B. Creating state of the art, next-generation virtual reality exposure therapies for anxiety disorders using consumer hardware platforms: design considerations and future directions. Cogn. Behav. Ther. 2017; 46 (5): 404–420. DOI: 10.1080/16506073.2017.1280843.

27. Cárdenas-López G., de la Rosa A., Durón R., Durán X. Virtual reality exposure for trauma and stress-related disorders for city violence crime victims. International Journal of Child Health and Human Development. 2016; 9 (3): 315–322.

28. Reger G.M., Koenen-Woods P., Zetocha K., Smolenski D.J., Holloway K.M., Rothbaum B.O. Randomized controlled trial of prolonged exposure using imaginal exposure vs. virtual reality exposure in active duty soldiers with deployment-related posttraumatic stress disorder (PTSD). J. Consult. Clin. Psychol. 2016; 84 (11): 946–959.

29.  Rothbaum B.O., Price M., Jovanovic T., Norrholm S.D., Gerardi M., Dunlop B. A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans. Am. J. Psychiatry. 2014; 171 (6): 640–648.

30.  Padrino-Barrios C., McCombs G., Diawara N., De Leo G. The use of immersive visualization for the control of dental anxiety during oral debridement. J. Dent. Hyg. 2015; 89 (6): 372–377.

31.  Freeman D., Antley A., Ehlers A., Dunn G., Thompson C., Vorontsova N. The use of immersive virtual reality (VR) to predict the occurrence 6 months later of paranoid thinking and posttraumatic stress symptoms assessed by self-report and interviewer methods: a study of individuals who have been physically assaulted. Psychol. Assess. 2014; 26 (3): 841–847.

32. Veling W., Counotte J., Pot-Kolder R., van Os J., van der Gaag M. Childhood trauma, psychosis liability and social stress reactivity: a virtual reality study. Psychol. Med. 2016; 46 (16): 3339–3348.

33. Dascal J., Reid M., IsHak W.W., Spiegel B., Recacho J., Rosen B., Danovitch I. Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials. Innov. Clin. Neurosci. 2017; 14 (1–2): 14–21.

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Поступила в редакцию 30.06.2020; принята 12.09.2020.

 

Авторский коллектив

Бофанова Наталия Сергеевна – кандидат медицинских наук, доцент кафедры неврологии, нейрохирургии и психиатрии, ФГБОУ ВО «Пензенский государственный университет». 440026, Россия, г. Пенза, ул. Красная, 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-5455-4987.

Петрова Елена Владимировна – кандидат медицинских наук, доцент, заведующая кафедрой неврологии, нейрохирургии и психиатрии, ФГБОУ ВО «Пензенский государственный университет». 440026, Россия, г. Пенза, ул. Красная, 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-5941-8300.

Калистратов Владимир Борисович – кандидат медицинских наук, доцент кафедры неврологии, нейрохирургии и психиатрии, ФГБОУ ВО «Пензенский государственный университет». 440026, Россия, г. Пенза, ул. Красная, 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-5851-857X.

Нестеренко Евгений Николаевич – кандидат исторических наук, старший преподаватель кафедры неврологии, нейрохирургии и психиатрии, ФГБОУ ВО «Пензенский государственный университет». 440026, Россия, г. Пенза, ул. Красная, 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-8990-3454.

Чиж Дарья Ивановна – ассистент кафедры неврологии, нейрохирургии и психиатрии, ФГБОУ ВО «Пензенский государственный университет». 440026, Россия, г. Пенза, ул. Красная, 40; e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра., ORCID ID: http://orcid.org/0000-0002-9958-4426.

 

Образец цитирования

Бофанова Н.С., Петрова Е.В., Калистратов В.Б., Нестеренко Е.Н., Чиж Д.И. Применение технологии виртуальной реальности для лечения болевого синдрома у детей. Ульяновский медико-биологический журнал. 2020; 4: 19–29. DOI: 10.34014/2227-1848-2020-4-19-29.