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ACUTE KIDNEY INJURY IN PATIENTS WITH ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION

M.V. Menzorov, A.M. Shutov, V.A. Serov, E.V. Mihailova

Ulyanovsk State University

 

The purpose of this study was to examine the incidence of the acute kidney injury (AKI), defined by the RIFLE criteria and the AKIN criteria in patients with ST-segment elevation acute myocardial infarction undergoing pharmacological reperfusion. Creatinine criteria led to a maximum RIFLE and a maximum AKIN in 51 % and 59 % of patients, respectively. Urine output criteria led to a maximum RIFLE and a maximum AKIN in 35 % of patients. AKI defined by urine output criteria was associated with inhospital mortality.

Keywords: body composition, body mass index, fat body weight, total body water, index total body water, atrial fibrillation.

 

References

  1. Национальные рекомендации по диагностике и лечению больных острым инфарктом миокарда с подъемом сегмента ST ЭКГ // Кардиоваскулярная терапия и профилактика. – 2007. – №6. – Прил. 1.

  2. Смирнов, А.В. Острое повреждение по-чек – новое понятие в нефрологии / А.В. Смирнов, И.Г. Каюков, В.А. Добронравов и др. // Клиническая нефрология. – 2009. – №1. – С. 11–15.

  3. Шутов, А.М. Митральная регургитация у больных с хронической сердечной недостаточностью ассоциирована со снижением функционального состояния почек / А.М. Шутов, Е.В. Курзина, В.А. Серов и др. // Нефрология. – 2008. – №12. – C. 19–23.

  4. Bagshaw, S.M. A comparison of the RIFLE and AKIN criteria for acute kidney injury in critically ill patients / S.M. Bagshaw, C. George, R. Bellomo // Nephrol Dial Transplant. – 2008. – V. 23. – P. 1569–1574.

  5. Basu, G. Acute kidney injury in tropical acute febrile illness in a tertiary care centre – RIFLE criteria validation / G. Basu, A. Chrispal, H. Boorugu et al. // Nephrol Dial Transplant. – 2011. – V. 26. – P. 524–531.

  6. Bellomo, R. Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group / R. Bellomo, C. Ronco, J.A. Kellum et al. // Crit. Care. – 2004. – V. 8. – P. 204–212.

  7. Biesen, W.V. Defining acute kidney injury: playing hide-and-seek with the unknown man? / W.V. Biesen, J.V. Massenhove, E. Hoste et al. // Nephrol. Dial. Transplant. – 2011. – V. 26. – P. 399–401.

  8. Chenoweth, C.E. Urinary tract infections / C.E. Chenoweth, S. Saint // Infectious Disease Clinics of North America. – 2011. – V. 25. – P. 103–115.

  9. Englberger, L. Clinical accuracy of RIFLE and Acute Kidney Injury Network (AKIN) criteria for acute kidney injury in patients undergoing cardiac surgery / L. Englberger, R.M. Suri, Z. Li et al. // Crit. Care. – 2011. – V. 15. – P. 16.

  10. Goldberg, A. In-hospital and 1-year mortality of patients who develop worsening renal function following acute ST-elevation myocardial infarction / A. Goldberg, H. Hammerman, S. Petcherski et al. // Am. Heart J. – 2005. – V. 150. – P. 330–337.

  11. Leblanc, M. Risk factors for acute renal failure: inherent and modifiable risks / M. Leblanc, J.A. Kellum, R.T. Gibney et al. // Curr. Opin. Crit. Care. – 2005. – V. 11. – P. 533–536.

  12. Macedo, E. Defining urine output criterion for acute kidney injury in critically ill patients / E. Macedo, R. Malhotra, R. Claure-Del Granado et al. // Nephrol. Dial. Transplant. – 2011. – V. 26. – P. 509–515.

  13. Mahesh, B. Does furosemide prevent renal dysfunction in high-risk cardiac surgical patients? Results of a double-blinded prospective randomised trial / B. Mahesh, B. Yim, D. Robson et al. // Eur. J. Cardiothorac. Surg. – 2008. – V. 33. – P. 370–376.

  14. Marenzi, G. Acute kidney injury in ST-segment elevation acute myocardial infarction complicated by cardiogenic shock at admission / G. Marenzi, E. Assanelli, J. Campodonico et al. // Crit. Care. Med. – 2010. – V. 38. – P. 438–444.

  15. Mehran, R. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation / R. Mehran, E.D. Aymong, E. Nikolsky et al. // J. Am. Coll. Cardiol. – 2004. – V. 44. – P. 1393–1399.

  16. Mehta, R.L. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury / R.L. Mehta, J.A. Kellum, S. Shah et al. // Crit. Care. – 2007. – V. 11. – P. 31.

  17. Parikh, C.R. Long-term Prognosis of Acute Kidney Injury After Acute Myocardial Infarction / C.R. Parikh, S.G. Coca, Y. Wang et al. // Arch. Intern. Med. – 2008. – V. 168. – P. 987–995.

  18. Shavit, L. Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Complications and Mortality in Patients Undergoing Non-Cardiac Major Surgery / L. Shavit, I. Dolgoker, H. Ivgi et al. // Kidney Blood Press Res. – 2011. – V. 34. – P. 116–124.

 

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УДК 616.61:616.127-005.8.

ОСТРОЕ ПОВРЕЖДЕНИЕ ПОЧЕК У БОЛЬНЫХ ИНФАРКТОМ МИОКАРДА С ПОДЪЕМОМ СЕГМЕНТА ST

А.М. Шутов, М.В. Мензоров, В.А. Серов, Е.В. Михайлова

Ульяновский государственный университет

 

В работе изучены частота и выраженность острого повреждения почек (ОПП) по критериям RIFLE и AKIN у больных острым инфарктом миокарда с подъемом сегмента ST (ОИМпST). Обнаружено, что более половины больных ОИМпST имеют острое повреждение почек по критериям RIFLE и AKIN по креатинину сыворотки (RIFLECr, AKINCr). Частота ОПП по критериям RIFLE и AKIN по диурезу (RIFLEou и AKINou) на 40 % меньше по сравнению с оценкой по AKINCr и на треть меньше по сравнению с оценкой по RIFLECr. Наличие ОПП ассоциировано с отсутствием эффекта от тромболитической терапии и повышением внутригоспитальной летальности.

Ключевые слова: инфаркт миокарда, острое повреждение почек, критерии RIFLE, критерии AKIN, тромболизис.

 

Литература

  1. Национальные рекомендации по диагностике и лечению больных острым инфарктом миокарда с подъемом сегмента ST ЭКГ // Кардиоваскулярная терапия и профилактика. – 2007. – №6. – Прил. 1.

  2. Смирнов, А.В. Острое повреждение по-чек – новое понятие в нефрологии / А.В. Смирнов, И.Г. Каюков, В.А. Добронравов и др. // Клиническая нефрология. – 2009. – №1. – С. 11–15.

  3. Шутов, А.М. Митральная регургитация у больных с хронической сердечной недостаточностью ассоциирована со снижением функционального состояния почек / А.М. Шутов, Е.В. Курзина, В.А. Серов и др. // Нефрология. – 2008. – №12. – C. 19–23.

  4. Bagshaw, S.M. A comparison of the RIFLE and AKIN criteria for acute kidney injury in critically ill patients / S.M. Bagshaw, C. George, R. Bellomo // Nephrol Dial Transplant. – 2008. – V. 23. – P. 1569–1574.

  5. Basu, G. Acute kidney injury in tropical acute febrile illness in a tertiary care centre – RIFLE criteria validation / G. Basu, A. Chrispal, H. Boorugu et al. // Nephrol Dial Transplant. – 2011. – V. 26. – P. 524–531.

  6. Bellomo, R. Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group / R. Bellomo, C. Ronco, J.A. Kellum et al. // Crit. Care. – 2004. – V. 8. – P. 204–212.

  7. Biesen, W.V. Defining acute kidney injury: playing hide-and-seek with the unknown man? / W.V. Biesen, J.V. Massenhove, E. Hoste et al. // Nephrol. Dial. Transplant. – 2011. – V. 26. – P. 399–401.

  8. Chenoweth, C.E. Urinary tract infections / C.E. Chenoweth, S. Saint // Infectious Disease Clinics of North America. – 2011. – V. 25. – P. 103–115.

  9. Englberger, L. Clinical accuracy of RIFLE and Acute Kidney Injury Network (AKIN) criteria for acute kidney injury in patients undergoing cardiac surgery / L. Englberger, R.M. Suri, Z. Li et al. // Crit. Care. – 2011. – V. 15. – P. 16.

  10. Goldberg, A. In-hospital and 1-year mortality of patients who develop worsening renal function following acute ST-elevation myocardial infarction / A. Goldberg, H. Hammerman, S. Petcherski et al. // Am. Heart J. – 2005. – V. 150. – P. 330–337.

  11. Leblanc, M. Risk factors for acute renal failure: inherent and modifiable risks / M. Leblanc, J.A. Kellum, R.T. Gibney et al. // Curr. Opin. Crit. Care. – 2005. – V. 11. – P. 533–536.

  12. Macedo, E. Defining urine output criterion for acute kidney injury in critically ill patients / E. Macedo, R. Malhotra, R. Claure-Del Granado et al. // Nephrol. Dial. Transplant. – 2011. – V. 26. – P. 509–515.

  13. Mahesh, B. Does furosemide prevent renal dysfunction in high-risk cardiac surgical patients? Results of a double-blinded prospective randomised trial / B. Mahesh, B. Yim, D. Robson et al. // Eur. J. Cardiothorac. Surg. – 2008. – V. 33. – P. 370–376.

  14. Marenzi, G. Acute kidney injury in ST-segment elevation acute myocardial infarction complicated by cardiogenic shock at admission / G. Marenzi, E. Assanelli, J. Campodonico et al. // Crit. Care. Med. – 2010. – V. 38. – P. 438–444.

  15. Mehran, R. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation / R. Mehran, E.D. Aymong, E. Nikolsky et al. // J. Am. Coll. Cardiol. – 2004. – V. 44. – P. 1393–1399.

  16. Mehta, R.L. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury / R.L. Mehta, J.A. Kellum, S. Shah et al. // Crit. Care. – 2007. – V. 11. – P. 31.

  17. Parikh, C.R. Long-term Prognosis of Acute Kidney Injury After Acute Myocardial Infarction / C.R. Parikh, S.G. Coca, Y. Wang et al. // Arch. Intern. Med. – 2008. – V. 168. – P. 987–995.

  18. Shavit, L. Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Complications and Mortality in Patients Undergoing Non-Cardiac Major Surgery / L. Shavit, I. Dolgoker, H. Ivgi et al. // Kidney Blood Press Res. – 2011. – V. 34. – P. 116–124.